1. Health/Hospital  Impacts and Resource Issues
          a. Pharmaceuticals
          b. Medical and other materials
          c. Hospital capacity issues
          d. Staff availability
          e. Availability of essential services, power, fuel (including for backup generators, ambulances, etc.
           f. Critical vendor availability (elevator and equipment maintenance; technical assistance, food service, janitorial services, EMS; power generators—availability and technicians)
         g. Hospital related public safety and security issues
         h. Personal Protective Equipment
          i. Alternative Care Facilities
          j. Other issues

2. Public Health/Healthcare Policy Issues
          a. Level of key stakeholder understanding of pandemic and other bio-event-related health impacts and preparedness needs (e.g., radiological/nuclear, earthquakes, other major all-hazards disasters)
          b. Effectiveness of preparedness plans
          c. Prioritized distribution of vaccinations/anti-virals, other medical/hygiene supplies, and related issues
          d. Determination of essential personnel for anti-virals
          e. Surge capability for hospitals in a pandemic or other bio-event
           f. Lab analysis capabilities
          g. Continued operation of pharmaceutical companies/retailers, grocery stores
          h. Pay for vaccines v. free distribution issues
           i. Sheltering during a disaster during a pandemic or other bio-event
           j. School closure/Daycare issues
          k. Business closures
           l. Event cancellations (e.g., sports events, other)
        m. Social Distancing
         n. Travel restrictions (local, domestic, international)
         o. Quarantines/cohorting (particularly related to air and sea travel)
         p. Insurance Issues
         q. National border-crossing issues
          r. Credentialing/certification for access to restricted areas 
         s. Disinfection/Decontamination and related issues
          t. Mass fatalities Planning/mortuary-related issues
         u. Livestock issues
         v. Other issues

3. Communications, Critical IT Systems, Health Data Issues
         a. Alert and warning/notifications
         b. Messaging to schools and other institutions with significant populations
         c. Data Collection capabilities (availability, including international information; collection, coordination, dissemination)
         d. Information sharing issues (too much/rapidly changing/conflicting information; prioritization, integration of data, standardized approach/use of GIS)
         e.  Insurance Healthcare Data Systems
          f.  IT Systems reliability, resilience and security
         g. Telecommuting, including “last mile issue” and teleconferencing issues
         h. HIPPA restrictions on health information
          i. Availability of IT technical expertise (personnel shortages)
          j. Other

4. Response Issues
          a. Incident Management/Unified Command/Area Command
          b. Roles and Missions (Federal, State, Local, Private Sector and Community)
          c. Decision-Making (cross-jurisdiction, cross-sector, cross-discipline)
          d. Cooperation, Coordination, including cross-state and cross-national border, on plans, activities
          e. Security for vaccine distribution in transit and for dispensing organizations on site
           f. Security for grocery stores and pharmacies
          g. Cross-sector/cross-discipline Information-Sharing (effectiveness of mechanisms)
          h. Mutual aid agreements (cross-state and cross-border)
           i. Availability of Emergency Managers and First Responders
           j. Resource requirements and management
          k. Logistics and supplies availability
           l. Other Issues

5. Infrastructure and Associated Interdependencies Impacts, Risk Assessment and Mitigation
          a. Identification and prioritization of critical assets, interdependencies-related vulnerabilities and preparedness gaps
          b. Ensuring confidentially of propriety and sensitive information
          c. Assessment of potential and cascading impacts on infrastructures and essential services, including impediments to response and recovery
                    -Transportation
                    -Emergency Services,
                   - Energy, 
                   - Etc.
          d. Identification of potential mitigation measures
          e. Other Issues

6. Business Continuity, Continuity of Operations, and Supply Chain Management
          a. Identification of essential operations and business activities
          b. Assessment of potential disruptions to operational and business services, including logistics, suppliers, customers, availability of truck drivers, warehouses, etc.)
          c. Business liaisons in the ECC
          d. Identification of potential mitigation measures (e.g., relocation of services, redundant or back-up systems and personnel)
          e. Administrative, budget issues
           f. Workforce policy issues (compensation, absences, isolation and removal of potentially contagious employees, safe workplace rules, flexible payroll issues, etc.
          g. Economic consequences
          h. Assistance to small businesses for contingency planning/continuity of operations
           i. Involvement of broad range of businesses in bio-event preparedness activities
           j. Notification and provision of employee information
          k. Training of employees
           l. Testing of continuity plans and procedures
         m. Other

7. General Restoration Issues
          a. Restoration Management Structure—What organizations and how organized and Unified Command
          b. Roles and Missions (Federal, State, Local, Private Sector and Community)
          c. Decision-Making (cross-jurisdiction, cross-sector, cross-discipline)
          d. Cooperation, coordination
          e. Prioritization of Service Restoration
           f. Resource requirements and management
          g. Other issues

8. Human Factors, Community and Family Issues
          a. Understanding and dealing with psychological impacts
          b. Identifying and addressing family assistance needs
          c. Education academic institutions (daycare centers, schools, colleges and universities, libraries, community centers)
          d. Special needs populations and ethnic and cultural groups
          e. Other

9. Legal and liability issues
          a. For government agencies
          b. For businesses (employee, insurance, contractual issues, information from/coordination with regulators)
          c. Privacy issues
          d. Ethical issues
          e. Union-related issues
           f. Liability associated with vaccine distribution and administering
          g. Other

10. Public Information, including Media
          a. What information to convey, how (regional coordination process and mechanisms), and who is the spokesperson?
          b. Maintenance of public confidence
          c. Outreach to and information to area businesses
          d. Outreach to and information for cultural and religious groups
          e. Utilization of social networks
           f. Involvement of media as partner in preparedness
          g. Other

11. Training, Exercises and Education
          a. Target audiences
          b. Tools (course curriculum, webinars, workshops, train the trainers, etc...)
          c. Resources needed and availability
          d. NIMS/ICS training for private sector organizations
          e. Focus on training from “business” perspective, not government
           f. Inclusion of private sector organizations in full-scale exercises

12. Financial Issues (funding/reimbursement)
          a. Private Sector
          b. Federal, State and Local Governments
          c. Non-Profit and Community Organizations
          d. For implementation of prevention, mitigation, and other CCBER resilience requirements
          e. Loans and incentives to small and medium businesses for bio-event preparedness
           f. Other